9.00 – 11.00 New mechanistic insights in tumorigenesis (I)
Chairs: Ulrich Maurer, Michael Hahne
09.00 – 09.15 Valeria Lascano: APRIL enhances tumor formation in mouse models of colorectal cancer and correlates with poor survival of patients
09.15 – 09.30 Martijn H.A. van Attekum: TNF-family members BAFF and APRIL confer survival and drug resistance in Chronic Lymphocytic Leukemia in novel models of the lymph node microenvironment
09.30 – 09.45 Ulrich Maurer: The role of MCL-1 phosphorylation for lymphocyte development and Myc-induced lymphomagenesis
09.45 – 10.00 Sabine Spinner: The role of the anti-apoptotic Bcl-2 proteins Bcl-xL and Mcl-1 in survival of thymic T-cell derived Non-Hodgkin lymphoma
10.00 – 10.15 Inga Melzer: The antiapoptotic protein Aven is involved in murine mammary gland development and breast cancer initiation/maintenance
10.15 – 10.30 Carmen Palacios: Control of FLIPL expression and TRAIL resistance by the extracellular signal-regulated kinase (ERK)1/2 pathway in breast epithelial cells
10.30 – 11.00 Coffee break
11.00 – 12.15 New mechanistic insights in tumorigenesis (II)
Chairs: Jan Paul Medema, Huseyin Mehmet
11.00 – 11.15 Lukas Peintner: Investigating the role of RAIDD in Caspase-2-dependent tumor suppression
11.15 – 11.30 Sara Pensa: The PI3K regulatory subunits p50alpha and p55alpha regulate cell death in vivo
11.30 – 11.45 Mikkel Rohde: The role of heat shock protein 70-2 in alternative splicing in cancer cells
11.45 – 12.00 Bettina Schwamb: FAM96A is a regulator of the intrinsic apoptosis pathway and involved in tumorigenesis of gastrointestinal stromal tumors
12.00 – 12.15 Sonja Aits: Identification of cytoskeleton-associated proteins essential for cancer cell survival and lysosomal stability
12.30 – 13.30 Lunch
Free afternoon
Rafting: 1st group 13.30 – 15.00, 2nd group 15.00 – 16.30, 3rd group 16.30 – 18.00 (pick-up from hotel)
Mountain biking: Start 16.00 – Return 19.00 (pick-up from hotel)
Hiking: Start 14.30 from parking Les Bains (close to Seminar room la salle du dôme), return 17.30 at the latest
19.30 Bus pick-up from hotel to go to Puy St. Vincent, followed by 10 min walk to Chalet le Pralong
20.00 – 22.00 Special dinner with view on the old town of Briançon