7:00 – 9:00 Breakfast

9:00 – 10:15 Caspases & Death domain folds (Lisa Bouchier-Hayes / Brian Ferguson)

Susan Logue: Proteomics–based identification of novel substrates for the inflammatory caspases

Maarten Hoek: Identification of proteolytic events in the membrane fraction of apoptotic cells using a quantitative proteomics approach

Brian Ferguson: AIRE and SP100 define a novel nuclear family of CARD proteins

Lisa Bouchier-Hayes: Real-time Detection of Caspase-2 Dimerization using Bimolecular Fluorescence Complementation

Claudia Manzl: Investigating the role of PIDD in DNA damageinduced apoptosis and DNA repair

 

10:15 – 11:00 coffee break

11:00 – 12:15 Lymphocyte-associated Death (Nigel Waterhouse / Dirk Brenner)

Nigel J. Waterhouse: Maintaining the pressure to die; cytotoxic lymphocytes trigger signalling pathways that persist although the initial stimulus is removed

Daniel Hostetter: Tipping the scales of life and death: new modes of Granzyme B-induced apoptosis

Patricia S. Hähnel: Targeting protein kinase B/AKT to reverse resistance against immune-mediated tumor suppression

Dirk Brenner: Regulation of activation-induced cell death by T cell receptor-proximal signalling

Katharina Lückerath: Analysis of knock-out/knock-in mice that express a mutant FasL lacking the intracellular domain

 

12:15 – 14:00 lunch

14:00 – 15:15 Alternative pathways (Cristina Munoz-Pinedo / Brent Derry)

Brent Derry: Regulation of germline apoptosis by CCM genes kri- 1/KRIT1 and C14A4.11/PDCD10 in C. elegans

Mads Daugaard: Cancer cell survival factor LEDGF/p75 is a nuclear protein that mediates lysosomal stability

Frederic Mille: The Patched dependence receptor triggers apoptosis through a caspase–activating complex

Nele Vanlangenakker: RNAi screen reveals novel kinases involved in necrotic cell death

Alfredo Caro -Maldonado: A Bax/Bak–independent apoptotic pathway induced by glucose deprivation

 

15:15 – 16:00 coffee break

16:00 – 17:00 Death receptor-induced apoptosis (Tobias Haas / Martin Sprick)

Aura Kaunisto: Regulation of cell death by c-Flip phosphorylation

Tobias L. Haas: Identification of novel constituents of the TNF receptor signalling complex

Inge Verbrugge: Sensitizing tumor cells to death receptorinduced apoptosis: is “stress” signalling the key?

Christina Falschlehner: Identification of novel components of the TRAIL apoptosis pathway by genome-wide RNA interference

 

17:00 – 20:00 Poster Session II (presenting authors: M-Z)

20:00 – 22:00 Dinner