7:30-8:15 Breakfast
8:30-10:20 Session VIII: Transcriptional regulation of apoptosis (E. Baehrecke/A. Sala)
Eric Baehrecke: Steroid regulation of programmed cell death during Drosophila development.
Eva Szegezdi: Natural retinoic acids inhibit the activation induced T-cell death by modifying the function of Nur77.
Arturo Sala: Apolipoprotein J (Clusterin), a protein required for neuroblastoma cell survival, is directly regulated by the B-myb oncoprotein and expressed in advanced disease stages.
Ann Zeuner: Interferon regulatory factor-1 and -2 regulate constitutive and interferon-gamma-induced expression of multiple caspases in monocytic cells.
Adriana Eramo: Caspase mediated TAL-1 cleavage is required for erythroid cell apoptosis.
Christopher Stroh: Novel approach for enhancing the susceptibility of cancer cells to chemotherapeutic drug induced apoptosis: inhibition of NF-kB through intracellular delivery of IkB by HSV-1 structural protein VP22.
10:20-10:50 Coffee break
10:50-13:00 Session IX: Anti- and pro-apoptotic mechanisms (M. Jäättelä/T. Brunner)
Marco vanEijk: Follicular dendritic cells provide GC B cells with two anti-apoptotic signals.
LorettaTuosto: Engagement of CD4 before TCR triggering regulates both Bax- and Fas-mediated apoptosis.
Wanjun Chen: Requirement for transforming growth factor-beta-1 (TGF-b1) in controlling T cell apoptosis.
Stefanie Tran: MAP Kinase-mediated regulation of FAS, TNF and TRAIL receptor-induced apoptosis in HELA cells.
Francesca Bernassola: Charachterization of TGase-2 KO mice.
Nils Holler: FLIP activates NF-kB and ERK signaling pathways and can divert Fas ligand-induced death signals to survival.
Frank Neumann: The pro- and anti- apoptotic properties of cFLIP short depend upon its intracellular compartmentalisation.
13:00-14:30 Lunch at conference site
14:30-15:45 Session X: Heat Shock Proteins (M. Jäättelä/V. De Laurenzi)
Marja Jäättelä: Hsp70 protects tumour cells from cell death by at least two distinct mechanisms.
Fabio Martinon: Interaction of SODD with Hsp70/Hsc70 via the BAG domain.
Jesper Nylandsted: Inhibition of Hsp70 synthesis leads to apoptotic death of breast cancer cells.
15:45-16:15 Coffee break
16:15-18.20 Session XI: Apoptosis and tumors (M. Hahne/J.P. Medema)
Jan Paul Medema: Immune escape of tumors in vivo.
Jennifer Rohn: The role of a tumor-specific environment in the apoptotic activity of Apoptin.
Larry Denner: Engagement of the Apoptotic Machinery in Prostate Cancer.
Lucy Peltenburg: Molecular analysis of radiation-induced apoptosis in paraffin-embedded tumor and normal tissue of rectal cancer patients.
Luisa Granziero: Modulation of Survivin expression by CD40L in B-chronic lymphocytic leukemia (B-CLL).
Valerie Zimmermann: Protection against an non-immunogenic melanoma by vaccination with apoptotic tumor cells coupled with TNF-a.
18:20 Concluding remarks
19:00 Last Evening Party at the conference site