7:30-8:15 Breakfast 8:30-10:00 Session V: TRAIL Signaling (H. Walczak/J. Borst) Henning Walczak: TRAIL-induced apoptosis is not inhibited by overexpression of Bcl-2 or Bcl-XL. Juthathip Mongkolsapaya: Structure of the apoptosis inducing TRAIL-DR5 complex. Martin Sprick: Caspase-8 and FADD/Mort1 are necessary components of the TRAIL-R2 death-inducing signalling complex (DISC). Marion MacFarlane: Active effector caspases and cleaved cytokeratins […]
7:30-8:15 Breakfast 8:30-10:20 Session I: Caspases (S. Srinivasula/R. De Maria) Eric Eldering: BCR induced apoptosis is initiated by a zVAD insensitive protease which is under direct control of CD40. Srinivasa Srinivasula: A regulatory role for Apaf 1 in caspase 9 function. Colin Adrain:Â DRADD is a nuclear-localized death domain adaptor protein that binds caspase-9 and promotes […]
15:00-19:00 Registration in Gibilmanna Monastery 20.00 Dinner and Welcome Address in the Cathedral of Cefalu’