Thursday May 10th 2018
Breakfast 09:00 Session 11 – Necroptosis, death receptors and inflammation Chairs: Mads Gyrd-Hansen; Anja Krippner-Heidenreich Annette Jacobsen, Walter + Eliza Hall Institute of Medical Research Compound X is a novel inhibitor of necroptosis in human cell lines. Emma Petrie, Walter + Eliza Hall Institute of Medical Research Formation of active human MLKL oligomers is tightly […]
Wednesday May 9, 2018
Breakfast 09:00 Session 9 – Mitochondria – from powerhouse to slaughterhouse Chairs: Cristina Muñoz-Pinedo; Rachel Uren Ana J. Garcia-Saez, University of Tübingen Mechanistic differences in Bax and Bak oligomerization at the single molecule level Jerry Edward Chipuk, Icahn School of Medicine at Mount Sinai MDM2 integrates cellular respiration and apoptotic signaling through NDUFS1 and the […]
Tuesday May 8, 2018
Breakfast 09:00 Session 5 – TNF signaling and inflammation Chairs: Markus Rehm Morrison; Diana Panayotova-Dimitrova Yves Dondelinger, VIB Center for Inflammation Research Phosphorylation of RIPK1 Ser25 controls TNF-induced cell death and inflammation Gianmaria Liccardi, Institute of Cancer Research RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development Joanna Fox, MRC Toxicology Unit Molecular Architecture and Mechanism […]
Monday May 7, 2018
Breakfast 9:00 – 9:15 Introduction/welcome 09:15 Session 1 – Tumorigenesis Chairs: Mads Daugaard; Peter Kreuzaler Kai Cao, University of Glasgow Apoptosis as an oncogenic driver – mechanism and impact on cancer Thomas Kaufmann, University of Bern Role of BOK in Cancer Yuchen Guo, University of Montpellier The role of cyclin A2 in colon homeostasis and […]