Friday 14th May

7.30 – 9.00:  Breakfast 9.00 – 10.45: p53 and Family Members (Eric Eldering and Arturo Sala) Jerry Chipuk: Direct Activation Of Bax By p53 Mediates Mitochondrial Membrane Permeabilization And Apoptosis. W. Brent Derry: Assembling the p53 network in C. elegans by functional genomics. Anastasis Stephanou: STAT1: a novel regulator of the apoptotic programme. Miriam Erlacher: […]

Thursday 13th May

7.30 – 9.00:  Breakfast 9.00 – 11.00: Immunology and Inflammation (Jan Paul Medema and John Silke) Douglas Green: A Physiological Function for TRAIL. Katharina Simon: Fas Ligand (FasL): an adjuvant to generate monoclonal antibodies that reject tumour . Lages Alves: Early induction of BH3-only protein Noxa in naïve CD8+ T cells after TCR triggering. Michel […]

Wednesday 12th May

7.30 – 9.00:  Breakfast 9.00 – 11.00: Caspase-independent Death (Eric Baehrecke and Christophe Borner) Stephen Tait: Caspase-independent cleavage of Bid at aspartate is essential for DNA damage-induced apoptosis. Lucy Peltenburg: A serine protease is involved in the initiation of DNA damage-induced apoptosis. Lotti Egger: Caspase-independent, apoptosis-like cell death and phagocytosis mediated by serine proteases. Colin Adrain: […]

Wednesday February 27th

8:00 – 9:00 Breakfast 9:30 – 11:15 Cell death in the nervous system (Huseyin Mehmet, Klaus Schulze-Osthoff) Flavia Troglio: The neuronal specific adaptor protein Rai (ShcC) inhibits apoptosis triggered by limited neurotrophic support or environmental stress by activating PI3K/Akt Adeline Lesay: BCL-2 PROTECTION FROM CYTOCHROME C-INDEPENDENT Apoptosis IN MAPLE SYRUP DISEASE Jacqueline Beesley: MUTANT PROTEOLIPID […]

Tuesday February 26th

8:00 – 9:00 Breakfast 9:15 – 11:00 Regulation of cell death 5: extracellular factors (Vincenzo De Laurenzi, Cristina Muñoz-Pinedo) Matilde Todaro: Th1and Th2 cytokines control cell survival in thyroid cancer by modulating apoptotic proteins Concetta Conticello: INTERLEUKIN-4 PROTECTS TUMOR CELLS FROM CD178 AND CHEMOTHERAPIC AGENTS VIA UPREGULATION OF ANTIAPOPTOTIC PROTEINS Igor Cima: IN SITU PRODUCTION […]

Monday February 25th

8:00 – 9:00 Breakfast 9:15 – 11:00 Regulation of cell death 2: by Bcl-2 family proteins (Jan Paul Medema, Marion MacFarlane) Andreas Villunger: BMF: A PROAPOPTOTIC BH3-ONLY PROTEIN REGULATED BY INTERACTION WITH THE MYOSIN V ACTIN MOTOR COMPLEX, ACTIVATED BY ANOIKIS Arlette Werner: DEFINING THE MECHANISM OF ACTION OF BFL-1,  A NOVEL INHIBITOR OF BID […]

Sunday February 24th

8:00 – 9:00 Breakfast 9:30 – 11:15   Expression and processing of TNF family members (Michel Hahne, Giorgio Stassi) Kerstin Herzer: MECHANISM OF TGF-ß INDUCED APOPTOSIS IN HEPATOMA CELLS Anne Grosse-Wilde: BIOCHEMICAL ANALYSIS OF MURINE TRAIL RECEPTORS Raymond Daniels: TRAIL and TRAIL receptor expression in normal and malignant tissues. Carmen Ruiz de Almodóvar: UP-REGULATION OF TRAIL […]

Tuesday April 4th

7:30-8:15 Breakfast 8:30-10:20 Session VIII: Transcriptional regulation of apoptosis (E. Baehrecke/A. Sala) Eric Baehrecke: Steroid regulation of programmed cell death during Drosophila development. Eva Szegezdi: Natural retinoic acids inhibit the activation induced T-cell death by modifying the function of Nur77. Arturo Sala: Apolipoprotein J (Clusterin), a protein required for neuroblastoma cell survival, is directly regulated […]